Three-dimensional decellularized tumor extracellular matrices with different stiffness as bioengineered tumor scaffolds
نویسندگان
چکیده
منابع مشابه
Printing three-dimensional tissue analogues with decellularized extracellular matrix bioink
The ability to print and pattern all the components that make up a tissue (cells and matrix materials) in three dimensions to generate structures similar to tissues is an exciting prospect of bioprinting. However, the majority of the matrix materials used so far for bioprinting cannot represent the complexity of natural extracellular matrix (ECM) and thus are unable to reconstitute the intrinsi...
متن کاملDevelopment of an Acellular Tumor Extracellular Matrix as a Three-Dimensional Scaffold for Tumor Engineering
Tumor engineering is defined as the construction of three-dimensional (3D) tumors in vitro with tissue engineering approaches. The present 3D scaffolds for tumor engineering have several limitations in terms of structure and function. To get an ideal 3D scaffold for tumor culture, A549 human pulmonary adenocarcinoma cells were implanted into immunodeficient mice to establish xenotransplatation ...
متن کاملPolyclonal Antibody against Different Extracellular Subdomains of HER2 Induces Tumor Growth Inhibition in vitro
Background: Human epidermal growth factor receptor 2 (HER2) has a crucial role in several malignancies. The extracellular domain of HER2 (HER2-ECD) has been extensively employed as an important target in passive and active immunotherapy. Isolated recombinant prokaryotic HER2-ECD subdomains were previously found to be ineffective in inducing anti-tumor antibody response. Objective: To employ rec...
متن کاملGeneration of bioengineered corneas with decellularized xenografts and human keratocytes.
PURPOSE Decellularization of animal corneas is a promising method for the development of artificial human corneas by tissue engineering. In this study, two different decellularization protocols were evaluated to determine which one is able to best preserve the histologic structure, composition, and optical behavior of decellularized porcine corneas. Then, these corneas were recellularized with ...
متن کاملKRUKENBERG TUMOR REPORT OF THREE CASES
Krukenberg tumor is an interesting and rare tumor which usually but not always is metastatic. Ovaries more than any other genital pelvic organs are the site of metastasis. Endometrium, gastrointestinal tract and breast are the most common primary sites. The best method of treatment is surgery. Postoperatively, radiotherapy and chemotherapy must be performed. 3 cases of Krukenberg tumor dia...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bioactive Materials
سال: 2021
ISSN: 2452-199X
DOI: 10.1016/j.bioactmat.2021.02.004